Identification of a 3-Alkylpyridinium Compound from the Red Sea Sponge Amphimedon chloros with In Vitro Inhibitory Activity against the West Nile Virus NS3 Protease

Viruses are underrepresented as targets in pharmacological screening efforts, given the difficulties of devising suitable cell-based and biochemical assays. In this study we found that a pre-fractionated organic extract of the Red Sea sponge Amphimedon chloros was able to inhibit the West Nile Virus...

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Detalles Bibliográficos
Autores principales: O’Rourke, Aubrie, Kremb, Stephan, Duggan, Brendan M., Sioud, Salim, Kharbatia, Najeh, Raji, Misjudeen, Emwas, Abdul-Hamid, Gerwick, William H., Voolstra, Christian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099703/
https://www.ncbi.nlm.nih.gov/pubmed/29912151
http://dx.doi.org/10.3390/molecules23061472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099703/
https://www.ncbi.nlm.nih.gov/pubmed/29912151
http://dx.doi.org/10.3390/molecules23061472

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