Investigations of Structural Requirements for BRD4 Inhibitors through Ligand- and Structure-Based 3D QSAR Approaches

The bromodomain containing protein 4 (BRD4) recognizes acetylated histone proteins and plays numerous roles in the progression of a wide range of cancers, due to which it is under intense investigation as a novel anti-cancer drug target. In the present study, we performed three-dimensional quantitat...

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Detalles Bibliográficos
Autores principales: Tahir, Adeena, Alharthy, Rima D., Naseem, Saadia, Mahmood, Natasha, Ahmed, Mahmood, Shahzad, Khuram, Akhtar, Malik Nadeem, Hameed, Abdul, Sadiq, Irfan, Nawaz, Haq, Muddassar, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099705/
https://www.ncbi.nlm.nih.gov/pubmed/29941841
http://dx.doi.org/10.3390/molecules23071527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099705/
https://www.ncbi.nlm.nih.gov/pubmed/29941841
http://dx.doi.org/10.3390/molecules23071527

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