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Investigations of Structural Requirements for BRD4 Inhibitors through Ligand- and Structure-Based 3D QSAR Approaches

The bromodomain containing protein 4 (BRD4) recognizes acetylated histone proteins and plays numerous roles in the progression of a wide range of cancers, due to which it is under intense investigation as a novel anti-cancer drug target. In the present study, we performed three-dimensional quantitat...

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Detalles Bibliográficos
Autores principales:	Tahir, Adeena, Alharthy, Rima D., Naseem, Saadia, Mahmood, Natasha, Ahmed, Mahmood, Shahzad, Khuram, Akhtar, Malik Nadeem, Hameed, Abdul, Sadiq, Irfan, Nawaz, Haq, Muddassar, Muhammad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099705/ https://www.ncbi.nlm.nih.gov/pubmed/29941841 http://dx.doi.org/10.3390/molecules23071527

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