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A Novel Class of Cationic and Non-Peptidic Small Molecules as Hits for the Development of Antimicrobial Agents

Cationic and non-peptide small molecules containing a total of six positive charges arranged on one side and a long aliphatic tail on the other have been synthesized and tested against Gram-positive and Gram-negative bacteria. The positive charges have been contributed by two aminophenol residues. T...

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Detalles Bibliográficos
Autores principales: Jiménez, Aranza, García, Pablo, de la Puente, Sofia, Madrona, Andrés, Camarasa, María José, Pérez-Pérez, María-Jesús, Quintela, José-Carlos, García-del Portillo, Francisco, San-Félix, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099707/
https://www.ncbi.nlm.nih.gov/pubmed/29932141
http://dx.doi.org/10.3390/molecules23071513