Cargando…

A Microdialysis in Adjuvant Arthritic Rats for Pharmacokinetics–Pharmacodynamics Modeling Study of Geniposide with Determination of Drug Concentration and Efficacy Levels in Dialysate

Microdialysis, a sampling method for pharmacokinetics–pharmacodynamics (PK–PD) modeling in preclinical and clinical studies, is a convenient in vivo sampling technique. Geniposide (GE), an iridoid glycoside compound, is the major active ingredient of Gardenia jasminoides Ellis fruit which has an ant...

Descripción completa

Detalles Bibliográficos
Autores principales: Deng, Ran, Wang, Wei, Wu, Hong, Zhang, Yunjing, Wang, Wenyu, Dai, Li, Zhang, Zhengrong, Fu, Jun, Li, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099731/
https://www.ncbi.nlm.nih.gov/pubmed/29695042
http://dx.doi.org/10.3390/molecules23050987