A Microdialysis in Adjuvant Arthritic Rats for Pharmacokinetics–Pharmacodynamics Modeling Study of Geniposide with Determination of Drug Concentration and Efficacy Levels in Dialysate

Microdialysis, a sampling method for pharmacokinetics–pharmacodynamics (PK–PD) modeling in preclinical and clinical studies, is a convenient in vivo sampling technique. Geniposide (GE), an iridoid glycoside compound, is the major active ingredient of Gardenia jasminoides Ellis fruit which has an ant...

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Detalles Bibliográficos
Autores principales: Deng, Ran, Wang, Wei, Wu, Hong, Zhang, Yunjing, Wang, Wenyu, Dai, Li, Zhang, Zhengrong, Fu, Jun, Li, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Essay
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099731/
https://www.ncbi.nlm.nih.gov/pubmed/29695042
http://dx.doi.org/10.3390/molecules23050987

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