Application of Docking Analysis in the Prediction and Biological Evaluation of the Lipoxygenase Inhibitory Action of Thiazolyl Derivatives of Mycophenolic Acid

5-LOX inhibition is among the desired characteristics of anti-inflammatory drugs, while 15-LOX has also been considered as a drug target. Similarity in inhibition behavior between soybean LOX-1 and human 5-LOX has been observed and soybean LOX (sLOX) type 1b has been used for the evaluation of LOX i...

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Detalles Bibliográficos
Autores principales: Tsolaki, Evangelia, Eleftheriou, Phaedra, Kartsev, Victor, Geronikaki, Athina, Saxena, Anil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099768/
https://www.ncbi.nlm.nih.gov/pubmed/29970872
http://dx.doi.org/10.3390/molecules23071621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099768/
https://www.ncbi.nlm.nih.gov/pubmed/29970872
http://dx.doi.org/10.3390/molecules23071621

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