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A Half-Century History of Applications of Antisense Oligonucleotides in Medicine, Agriculture and Forestry: We Should Continue the Journey

Antisense oligonucleotides (ASO), short single-stranded polymers based on DNA or RNA chemistries and synthesized in vitro, regulate gene expression by binding in a sequence-specific manner to an RNA target. The functional activity and selectivity in the action of ASOs largely depends on the combinat...

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Detalles Bibliográficos
Autores principales: Oberemok, Volodymyr V., Laikova, Kateryna V., Repetskaya, Anna I., Kenyo, Igor M., Gorlov, Mikhail V., Kasich, Igor N., Krasnodubets, Alisa M., Gal’chinsky, Nikita V., Fomochkina, Iryna I., Zaitsev, Aleksei S., Bekirova, Viktoriya V., Seidosmanova, Eleonora E., Dydik, Ksenia I., Meshcheryakova, Anna O., Nazarov, Sergey A., Smagliy, Natalya N., Chelengerova, Edie L., Kulanova, Alina A., Deri, Karim, Subbotkin, Mikhail V., Useinov, Refat Z., Shumskykh, Maksym N., Kubyshkin, Anatoly V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099785/
https://www.ncbi.nlm.nih.gov/pubmed/29844255
http://dx.doi.org/10.3390/molecules23061302