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p53-inducible DPYSL4 associates with mitochondrial supercomplexes and regulates energy metabolism in adipocytes and cancer cells

The tumor suppressor p53 regulates multiple cellular functions, including energy metabolism. Metabolic deregulation is implicated in the pathogenesis of some cancers and in metabolic disorders and may result from the inactivation of p53 functions. Using RNA sequencing and ChIP sequencing of cancer c...

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Detalles Bibliográficos
Autores principales: Nagano, Hidekazu, Hashimoto, Naoko, Nakayama, Akitoshi, Suzuki, Sawako, Miyabayashi, Yui, Yamato, Azusa, Higuchi, Seiichiro, Fujimoto, Masanori, Sakuma, Ikki, Beppu, Minako, Yokoyama, Masataka, Suzuki, Yutaka, Sugano, Sumio, Ikeda, Kazuhiro, Tatsuno, Ichiro, Manabe, Ichiro, Yokote, Koutaro, Inoue, Satoshi, Tanaka, Tomoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099896/
https://www.ncbi.nlm.nih.gov/pubmed/30061407
http://dx.doi.org/10.1073/pnas.1804243115