Synthesis and Biological Activity of Sterol 14α-Demethylase and Sterol C24-Methyltransferase Inhibitors

Sterol 14α-demethylase (SDM) is essential for sterol biosynthesis and is the primary molecular target for clinical and agricultural antifungals. SDM has been demonstrated to be a valid drug target for antiprotozoal therapies, and much research has been focused on using SDM inhibitors to treat neglec...

Descripción completa

Detalles Bibliográficos
Autor principal: Leaver, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099924/
https://www.ncbi.nlm.nih.gov/pubmed/30018257
http://dx.doi.org/10.3390/molecules23071753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099924/
https://www.ncbi.nlm.nih.gov/pubmed/30018257
http://dx.doi.org/10.3390/molecules23071753

Ejemplares similares