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Targeting General Transcriptional Machinery as a Therapeutic Strategy for Adult T-Cell Leukemia

Cancer cells are highly reliant on certain molecular pathways, which support their survival and proliferation. The fundamental concept of molecularly targeted therapy is to target a protein that is specifically deregulated or overexpressed in cancer cells. However, drug resistance and tumor heteroge...

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Detalles Bibliográficos
Autores principales: Wong, Regina Wan Ju, Ishida, Takashi, Sanda, Takaomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099935/
https://www.ncbi.nlm.nih.gov/pubmed/29724031
http://dx.doi.org/10.3390/molecules23051057