The Mechanism for siRNA Transmembrane Assisted by PMAL

The capacity of silencing genes makes small interfering RNA (siRNA) appealing for curing fatal diseases. However, the naked siRNA is vulnerable to and degraded by endogenous enzymes and is too large and too negatively charged to cross cellular membranes. An effective siRNA carrier, PMAL (poly(maleic...

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Detalles Bibliográficos
Autores principales: Lu, Yanfei, Li, Jipeng, Su, Nan, Lu, Diannan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099945/
https://www.ncbi.nlm.nih.gov/pubmed/29966273
http://dx.doi.org/10.3390/molecules23071586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099945/
https://www.ncbi.nlm.nih.gov/pubmed/29966273
http://dx.doi.org/10.3390/molecules23071586

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