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Garcinol Enhances TRAIL-Induced Apoptotic Cell Death through Up-Regulation of DR5 and Down-Regulation of c-FLIP Expression

Garcinol is a polyisoprenylated benzophenone derived from the Garcinia indica fruit that possess potential therapeutic effects such as inhibition of inflammation and tumor expansion. Here, we investigated whether garcinol induces TRAIL sensitization in renal carcinoma cells. Single treatment with ga...

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Detalles Bibliográficos
Autores principales: Kim, Seok, Seo, Seung Un, Min, Kyoung-Jin, Woo, Seon Min, Nam, Ju-Ock, Kubatka, Peter, Kim, Shin, Park, Jong-Wook, Kwon, Taeg Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099973/
https://www.ncbi.nlm.nih.gov/pubmed/30004456
http://dx.doi.org/10.3390/molecules23071614