Cargando…

Understanding the Role of Anti-PEG Antibodies in the Complement Activation by Doxil in Vitro

Infusion reactions (IRs) are common immune-mediated side effects in patients treated with a variety of drug products, including, but not limited to, nanotechnology formulations. The mechanism of IRs is not fully understood. One of the best studied mechanisms of IRs to nanomedicines is the complement...

Descripción completa

Detalles Bibliográficos
Autores principales: Neun, Barry W., Barenholz, Yechezkel, Szebeni, Janos, Dobrovolskaia, Marina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100003/
https://www.ncbi.nlm.nih.gov/pubmed/30002298
http://dx.doi.org/10.3390/molecules23071700