Indole Derivatives as Cyclooxygenase Inhibitors: Synthesis, Biological Evaluation and Docking Studies

A new series of 2-(5-methoxy-2-methyl-1H-indol-3-yl)-N′-[(E)-(substituted phenyl) methylidene] acetohydrazide derivatives (S1–S18) were synthesized and evaluated for their anti-inflammatory activity, analgesic activity, ulcerogenic activity, lipid peroxidation, ulcer index and cyclooxygenase express...

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Detalles Bibliográficos
Autores principales: Bhat, Mashooq Ahmad, Al-Omar, Mohamed A., Raish, Mohammad, Ansari, Mushtaq Ahmad, Abuelizz, Hatem A., Bakheit, Ahmed H., Naglah, Ahmed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100013/
https://www.ncbi.nlm.nih.gov/pubmed/29882911
http://dx.doi.org/10.3390/molecules23061250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100013/
https://www.ncbi.nlm.nih.gov/pubmed/29882911
http://dx.doi.org/10.3390/molecules23061250

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