Antitumor Effects and Delivery Profiles of Menahydroquinone-4 Prodrugs with Ionic or Nonionic Promoiety to Hepatocellular Carcinoma Cells

Hepatocellular carcinoma (HCC) shows poor prognosis owing to its very frequent recurrence even after curative treatment. Thus, an effective and safe long-term chemopreventive agent is strongly in demand. Menahydroquinone-4 (MKH) is an active form of menaquinone-4 (MK-4, vitamin K(2)) that is involve...

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Detalles Bibliográficos
Autores principales: Setoguchi, Shuichi, Watase, Daisuke, Matsunaga, Kazuhisa, Yamakawa, Hirofumi, Goto, Shotaro, Terada, Kazuki, Ohe, Kenji, Enjoji, Munechika, Karube, Yoshiharu, Takata, Jiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100056/
https://www.ncbi.nlm.nih.gov/pubmed/30013007
http://dx.doi.org/10.3390/molecules23071738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100056/
https://www.ncbi.nlm.nih.gov/pubmed/30013007
http://dx.doi.org/10.3390/molecules23071738

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