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The Cardioprotective Effect of Metformin in Doxorubicin-Induced Cardiotoxicity: The Role of Autophagy

The molecular mechanisms underlying doxorubicin-induced cardiotoxicity are still being investigated, but are known to involve oxidative stress, mitochondrial dysfunction, and the dysregulation of autophagy. The objective of the current study was to examine the protective role of metformin and its ef...

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Detalles Bibliográficos
Autores principales: Zilinyi, Rita, Czompa, Attila, Czegledi, Andras, Gajtko, Andrea, Pituk, Dora, Lekli, Istvan, Tosaki, Arpad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100061/
https://www.ncbi.nlm.nih.gov/pubmed/29762537
http://dx.doi.org/10.3390/molecules23051184