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The Cardioprotective Effect of Metformin in Doxorubicin-Induced Cardiotoxicity: The Role of Autophagy
The molecular mechanisms underlying doxorubicin-induced cardiotoxicity are still being investigated, but are known to involve oxidative stress, mitochondrial dysfunction, and the dysregulation of autophagy. The objective of the current study was to examine the protective role of metformin and its ef...
Autores principales: | Zilinyi, Rita, Czompa, Attila, Czegledi, Andras, Gajtko, Andrea, Pituk, Dora, Lekli, Istvan, Tosaki, Arpad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100061/ https://www.ncbi.nlm.nih.gov/pubmed/29762537 http://dx.doi.org/10.3390/molecules23051184 |
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