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The Keap1/Nrf2-ARE Pathway as a Pharmacological Target for Chalcones

Chalcones have shown a broad spectrum of biological activities with clinical potential against various diseases. The biological activities are mainly attributed to the presence in the chalcones of the α,β-unsaturated carbonyl system, perceived as a potential Michael acceptor. Chalcones could activat...

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Detalles Bibliográficos
Autores principales: de Freitas Silva, Matheus, Pruccoli, Letizia, Morroni, Fabiana, Sita, Giulia, Seghetti, Francesca, Viegas Jr, Claudio, Tarozzi, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100069/
https://www.ncbi.nlm.nih.gov/pubmed/30037040
http://dx.doi.org/10.3390/molecules23071803