Review on Abyssomicins: Inhibitors of the Chorismate Pathway and Folate Biosynthesis

Antifolates targeting folate biosynthesis within the shikimate-chorismate-folate metabolic pathway are ideal and selective antimicrobials, since higher eukaryotes lack this pathway and rely on an exogenous source of folate. Resistance to the available antifolates, inhibiting the folate pathway, unde...

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Detalles Bibliográficos
Autores principales: Sadaka, Carmen, Ellsworth, Edmund, Hansen, Paul Robert, Ewin, Richard, Damborg, Peter, Watts, Jeffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100094/
https://www.ncbi.nlm.nih.gov/pubmed/29882815
http://dx.doi.org/10.3390/molecules23061371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100094/
https://www.ncbi.nlm.nih.gov/pubmed/29882815
http://dx.doi.org/10.3390/molecules23061371

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