Poly(alkylidenimine) Dendrimers Functionalized with the Organometallic Moiety [Ru(η(5)-C(5)H(5))(PPh(3))(2)](+) as Promising Drugs Against Cisplatin-Resistant Cancer Cells and Human Mesenchymal Stem Cells

Here and for the first time, we show that the organometallic compound [Ru(η(5)-C(5)H(5))(PPh(3))(2)Cl] (RuCp) has potential to be used as a metallodrug in anticancer therapy, and further present a new approach for the cellular delivery of the [Ru(η(5)-C(5)H(5))(PPh(3))(2)](+) fragment via coordinati...

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Detalles Bibliográficos
Autores principales: Gouveia, Marisol, Figueira, João, Jardim, Manuel G., Castro, Rita, Tomás, Helena, Rissanen, Kari, Rodrigues, João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100097/
https://www.ncbi.nlm.nih.gov/pubmed/29914219
http://dx.doi.org/10.3390/molecules23061471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100097/
https://www.ncbi.nlm.nih.gov/pubmed/29914219
http://dx.doi.org/10.3390/molecules23061471

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