DDX3X RNA helicase affects breast cancer cell cycle progression by regulating expression of KLF4

DDX3X is a multifunctional RNA helicase with documented roles in different cancer types. Here, we demonstrate that DDX3X plays an oncogenic role in breast cancer cells by modulating the cell cycle. Depletion of DDX3X in MCF7 cells slows cell proliferation by inducing a G1 phase arrest. Notably, DDX3...

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Detalles Bibliográficos
Autores principales: Cannizzaro, Ester, Bannister, Andrew John, Han, Namshik, Alendar, Andrej, Kouzarides, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100109/
https://www.ncbi.nlm.nih.gov/pubmed/29782654
http://dx.doi.org/10.1002/1873-3468.13106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100109/
https://www.ncbi.nlm.nih.gov/pubmed/29782654
http://dx.doi.org/10.1002/1873-3468.13106

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