Novel Neuroprotective Lead Compound Ligustrazine Derivative Mass Spectrometry Fragmentation Rule and Metabolites in Rats by LC/LTQ-Orbitrap MS

The neuroprotective evaluation of ligustrazine derivatives has become a research focus all over the world. A novel ligustrazine derivative, (3,5,6-Trimethylpyrazin-2-yl)methyl(E)-3-(4-((3,5,6-trimethylpyrazin-2-l)methoxy)phenyl)acrylate (T-CA), has shown protective effects against CoCl(2)-induced ne...

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Detalles Bibliográficos
Autores principales: Zhang, Xinyu, Zhao, Rui, Chen, Meng, Ma, Tao, Wu, Gaorong, Xue, Nannan, Li, Guoliang, Wang, Hui, Fang, Kang, Zhang, Wenxi, Wang, Penglong, Lei, Haimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100194/
https://www.ncbi.nlm.nih.gov/pubmed/29751639
http://dx.doi.org/10.3390/molecules23051154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100194/
https://www.ncbi.nlm.nih.gov/pubmed/29751639
http://dx.doi.org/10.3390/molecules23051154

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