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Novel Neuroprotective Lead Compound Ligustrazine Derivative Mass Spectrometry Fragmentation Rule and Metabolites in Rats by LC/LTQ-Orbitrap MS
The neuroprotective evaluation of ligustrazine derivatives has become a research focus all over the world. A novel ligustrazine derivative, (3,5,6-Trimethylpyrazin-2-yl)methyl(E)-3-(4-((3,5,6-trimethylpyrazin-2-l)methoxy)phenyl)acrylate (T-CA), has shown protective effects against CoCl(2)-induced ne...
Autores principales: | Zhang, Xinyu, Zhao, Rui, Chen, Meng, Ma, Tao, Wu, Gaorong, Xue, Nannan, Li, Guoliang, Wang, Hui, Fang, Kang, Zhang, Wenxi, Wang, Penglong, Lei, Haimin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100194/ https://www.ncbi.nlm.nih.gov/pubmed/29751639 http://dx.doi.org/10.3390/molecules23051154 |
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