Structure-Dependent Activity of Natural GABA(A) Receptor Modulators

GABA(A) receptors are ligand-gated ion channels consisting of five subunits from eight subfamilies, each assembled in four hydrophobic transmembrane domains. This pentameric structure not only allows different receptor binding sites, but also various types of ligands, such as orthosteric agonists an...

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Detalles Bibliográficos
Autor principal: Çiçek, Serhat Sezai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100244/
https://www.ncbi.nlm.nih.gov/pubmed/29932138
http://dx.doi.org/10.3390/molecules23071512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100244/
https://www.ncbi.nlm.nih.gov/pubmed/29932138
http://dx.doi.org/10.3390/molecules23071512

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