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Structure-Dependent Activity of Natural GABA(A) Receptor Modulators
GABA(A) receptors are ligand-gated ion channels consisting of five subunits from eight subfamilies, each assembled in four hydrophobic transmembrane domains. This pentameric structure not only allows different receptor binding sites, but also various types of ligands, such as orthosteric agonists an...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100244/ https://www.ncbi.nlm.nih.gov/pubmed/29932138 http://dx.doi.org/10.3390/molecules23071512 |