Cargando…

Preparation of Enzyme-Activated Thapsigargin Prodrugs by Solid-Phase Synthesis

Since cells in solid tumors divide less rapidly than cells in the bone marrow or cells of the immune system, mitotic inhibitors often cause severe side effects when used for treatment of diseases like prostate cancer and breast cancer. One approach to overcome this problem involves attempts at devel...

Descripción completa

Detalles Bibliográficos
Autores principales: Zimmermann, Tomas, Christensen, Søren Brøgger, Franzyk, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100299/
https://www.ncbi.nlm.nih.gov/pubmed/29914143
http://dx.doi.org/10.3390/molecules23061463