Synthesis of a Reactive Oxygen Species-Responsive Doxorubicin Derivative

A heterobifunctional reactive oxygen species (ROS)-responsive linker for directed drug assembly onto and delivery from a quantum dot (QD) nanoparticle carrier was synthesized and coupled to doxorubicin using N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride (EDC)/sulfo–NHS coupling. The d...

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Detalles Bibliográficos
Autores principales: Delehanty, James B., Das, Shivani, Goldberg, Efram, Sangtani, Ajmeeta, Knight, D. Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100310/
https://www.ncbi.nlm.nih.gov/pubmed/30037071
http://dx.doi.org/10.3390/molecules23071809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100310/
https://www.ncbi.nlm.nih.gov/pubmed/30037071
http://dx.doi.org/10.3390/molecules23071809

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