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Anti-Proliferative Activity of HPOB against Multiple Myeloma Cells via p21 Transcriptional Activation

Histone acetylation or deacetylation is closely associated with the progression of multiple myeloma (MM). Currently, many histone deacetylase (HDAC) inhibitors have been approved for being used in clinical trials, but theirtherapeutic effectsarestill not ideal. As a novel HDAC inhibitor, hydroxamica...

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Detalles Bibliográficos
Autores principales: Liu, Linlin, Sun, Xiaoyang, Xie, Yu, Zhuang, Yinping, Yao, Ruosi, Xu, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100322/
https://www.ncbi.nlm.nih.gov/pubmed/29710846
http://dx.doi.org/10.3390/molecules23051044