Design and Synthesis of Lactams Derived from Mucochloric and Mucobromic Acids as Pseudomonas aeruginosa Quorum Sensing Inhibitors

Bacterial infections, particularly hospital-acquired infections caused by Pseudomonas aeruginosa, have become a global threat with a high mortality rate. Gram-negative bacteria including P. aeruginosa employ N-acyl homoserine lactones (AHLs) as chemical signals to regulate the expression of pathogen...

Descripción completa

Detalles Bibliográficos
Autores principales: Almohaywi, Basmah, Taunk, Aditi, Wenholz, Daniel S., Nizalapur, Shashidhar, Biswas, Nripendra N., Ho, Kitty K. K., Rice, Scott A., Iskander, George, Black, David StC., Griffith, Renate, Kumar, Naresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100351/
https://www.ncbi.nlm.nih.gov/pubmed/29735954
http://dx.doi.org/10.3390/molecules23051106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100351/
https://www.ncbi.nlm.nih.gov/pubmed/29735954
http://dx.doi.org/10.3390/molecules23051106

Ejemplares similares