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Design and Synthesis of Lactams Derived from Mucochloric and Mucobromic Acids as Pseudomonas aeruginosa Quorum Sensing Inhibitors
Bacterial infections, particularly hospital-acquired infections caused by Pseudomonas aeruginosa, have become a global threat with a high mortality rate. Gram-negative bacteria including P. aeruginosa employ N-acyl homoserine lactones (AHLs) as chemical signals to regulate the expression of pathogen...
Autores principales: | Almohaywi, Basmah, Taunk, Aditi, Wenholz, Daniel S., Nizalapur, Shashidhar, Biswas, Nripendra N., Ho, Kitty K. K., Rice, Scott A., Iskander, George, Black, David StC., Griffith, Renate, Kumar, Naresh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100351/ https://www.ncbi.nlm.nih.gov/pubmed/29735954 http://dx.doi.org/10.3390/molecules23051106 |
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