Potential Mechanism of Action of Cyclosporin A in Human Dermal Fibroblasts—Transcriptomic Analysis of CYPs

Effect of cyclosporin A (CsA) in a therapeutic concentration, on the expression of cytochrome P450 genes (CYPs), was investigated in normal human dermal fibroblast cells. The expression of 57 genes, encoding cytochrome P450 isoforms, was estimated using the microarray method. Amongst 396 normalized...

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Detalles Bibliográficos
Autores principales: Janikowska, Grażyna, Pyka-Pająk, Alina, Janikowski, Tomasz, Adamska, Jolanta, Mazurek, Urszula, Jędrusik, Przemysław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100361/
https://www.ncbi.nlm.nih.gov/pubmed/29976866
http://dx.doi.org/10.3390/molecules23071642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100361/
https://www.ncbi.nlm.nih.gov/pubmed/29976866
http://dx.doi.org/10.3390/molecules23071642

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