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Antiproliferative Phenothiazine Hybrids as Novel Apoptosis Inducers against MCF-7 Breast Cancer

We designed a series of novel phenothiazine-1,2,3-triazole hybrids by the molecular hybridization strategy and evaluated their antiproliferative activity against three cancer cell lines (MDA-MB-231, MDA-MB-468 and MCF-7). For the structure-activity relationships, the importance of 1,2,3-triazole and...

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Detalles Bibliográficos
Autores principales: Zhang, Jun-Xia, Guo, Jiao-Mei, Zhang, Ting-Ting, Lin, Hong-Jun, Qi, Nai-Song, Li, Zhen-Guo, Zhou, Ji-Chun, Zhang, Zhen-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100384/
https://www.ncbi.nlm.nih.gov/pubmed/29843370
http://dx.doi.org/10.3390/molecules23061288