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Protein Carriers for Glycoconjugate Vaccines: History, Selection Criteria, Characterization and New Trends

Currently licensed glycoconjugate vaccines are composed of a carbohydrate moiety covalently linked to a protein carrier. Polysaccharides are T-cell independent antigens able to directly stimulate B cells to produce antibodies. Disease burden caused by polysaccharide-encapsulated bacteria is highest...

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Detalles Bibliográficos
Autores principales: Micoli, Francesca, Adamo, Roberto, Costantino, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100388/
https://www.ncbi.nlm.nih.gov/pubmed/29914046
http://dx.doi.org/10.3390/molecules23061451