Strategies for Enhancing the Permeation of CNS-Active Drugs through the Blood-Brain Barrier: A Review

Background: The blood brain barrier (BBB) is a dynamic and functional structure which poses a vast challenge in the development of drugs acting on the central nervous system (CNS). While most substances are denied BBB crossing, selective penetration of substances mainly occurs through diffusion, car...

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Detalles Bibliográficos
Autores principales: Zeiadeh, Isra’, Najjar, Anas, Karaman, Rafik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100436/
https://www.ncbi.nlm.nih.gov/pubmed/29843371
http://dx.doi.org/10.3390/molecules23061289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100436/
https://www.ncbi.nlm.nih.gov/pubmed/29843371
http://dx.doi.org/10.3390/molecules23061289

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