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Strategies for Enhancing the Permeation of CNS-Active Drugs through the Blood-Brain Barrier: A Review

Background: The blood brain barrier (BBB) is a dynamic and functional structure which poses a vast challenge in the development of drugs acting on the central nervous system (CNS). While most substances are denied BBB crossing, selective penetration of substances mainly occurs through diffusion, car...

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Detalles Bibliográficos
Autores principales:	Zeiadeh, Isra’, Najjar, Anas, Karaman, Rafik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100436/ https://www.ncbi.nlm.nih.gov/pubmed/29843371 http://dx.doi.org/10.3390/molecules23061289

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