Design, Synthesis and Antitumor Evaluation of Novel Pyrazolopyrimidines and Pyrazoloquinazolines

A series of N-aryl-7-aryl-pyrazolo[1,5-a]pyrimidines 18a–u and N-aryl-pyrazolo[1,5-a]quinazolines 25a–c were designed and synthesized via the reaction of 5-aminopyrazoles 11a–c with enaminones 12a–g or 19, respectively. The new compounds were screened for their in vitro antitumor activity toward liv...

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Detalles Bibliográficos
Autores principales: El-Naggar, Mohamed, Hassan, Ashraf S., Awad, Hanem M., Mady, Mohamed F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100441/
https://www.ncbi.nlm.nih.gov/pubmed/29882908
http://dx.doi.org/10.3390/molecules23061249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100441/
https://www.ncbi.nlm.nih.gov/pubmed/29882908
http://dx.doi.org/10.3390/molecules23061249

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