Cargando…

In Vitro and In Vivo Anti-Breast Cancer Activities of Some Synthesized Pyrazolinyl-estran-17-one Candidates

A series of estrone derivatives, 2–4, were synthesized from the corresponding arylidine estrone, 2a,b, as starting materials, which were prepared by condensation of estrone (3-hydroxy-estran-17-one, 1) with 4-bromobenzaldehyde and thiophene-2-aldehyde. Treating of 2a,b with hydrazine derivatives in...

Descripción completa

Detalles Bibliográficos
Autores principales: Amr, Abd El-Galil E., El-Naggar, Mohamed, Al-Omar, Mohamed A., Elsayed, Elsayed Ahmed, Abdalla, Mohamed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100451/
https://www.ncbi.nlm.nih.gov/pubmed/29958453
http://dx.doi.org/10.3390/molecules23071572