Doxycycline Attenuates Atrial Remodeling by Interfering with MicroRNA-21 and Downstream Phosphatase and Tensin Homolog (PTEN)/Phosphoinositide 3-Kinase (PI3K) Signaling Pathway

BACKGROUND: Atrial remodeling especially in the form of fibrosis is the most important substrate of atrial fibrillation (AF). The aim of this study was to investigate the effects of doxycycline on chronic intermittent hypoxia (CIH)-induced atrial remodeling and the pathophysiological mechanisms unde...

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Detalles Bibliográficos
Autores principales: Zhang, Kai, Zhao, Linru, Ma, Zuowang, Wang, Weiding, Li, Xiongfeng, Zhang, Yue, Yuan, Meng, Liang, Xue, Li, Guangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100459/
https://www.ncbi.nlm.nih.gov/pubmed/30098136
http://dx.doi.org/10.12659/MSM.909800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100459/
https://www.ncbi.nlm.nih.gov/pubmed/30098136
http://dx.doi.org/10.12659/MSM.909800

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