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Fatty Acid-Stimulated Insulin Secretion vs. Lipotoxicity

Fatty acid (FA)-stimulated insulin secretion (FASIS) is reviewed here in contrast to type 2 diabetes etiology, resulting from FA overload, oxidative stress, intermediate hyperinsulinemia, and inflammation, all converging into insulin resistance. Focusing on pancreatic islet β-cells, we compare the p...

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Detalles Bibliográficos
Autores principales: Ježek, Petr, Jabůrek, Martin, Holendová, Blanka, Plecitá-Hlavatá, Lydie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100479/
https://www.ncbi.nlm.nih.gov/pubmed/29921789
http://dx.doi.org/10.3390/molecules23061483