Synthesis and Activity against Mycobacterium tuberculosis of Olivacine and Oxygenated Derivatives

The tetracyclic pyrido[4,3-b]carbazole olivacine and four of its oxygenated derivatives have been synthesized by a late-stage palladium-catalyzed Heck-type cyclization of the pyrrole ring as a key step. In a test for the inhibition of the growth of Mycobacterium tuberculosis, 9-methoxyolivacine show...

Descripción completa

Detalles Bibliográficos
Autores principales: Schmidt, Ulrike, Theumer, Gabriele, Jäger, Anne, Kataeva, Olga, Wan, Baojie, Franzblau, Scott G., Knölker, Hans-Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100493/
https://www.ncbi.nlm.nih.gov/pubmed/29890747
http://dx.doi.org/10.3390/molecules23061402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100493/
https://www.ncbi.nlm.nih.gov/pubmed/29890747
http://dx.doi.org/10.3390/molecules23061402

Ejemplares similares