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Salts of Therapeutic Agents: Chemical, Physicochemical, and Biological Considerations
The physicochemical and biological properties of active pharmaceutical ingredients (APIs) are greatly affected by their salt forms. The choice of a particular salt formulation is based on numerous factors such as API chemistry, intended dosage form, pharmacokinetics, and pharmacodynamics. The approp...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100526/ https://www.ncbi.nlm.nih.gov/pubmed/30011904 http://dx.doi.org/10.3390/molecules23071719 |