Triorganotin Derivatives Induce Cell Death Effects on L1210 Leukemia Cells at Submicromolar Concentrations Independently of P-glycoprotein Expression

The acceleration of drug efflux activity realized by plasma membrane transporters in neoplastic cells, particularly by P-glycoprotein (P-gp, ABCB1 member of the ABC transporter family), represents a frequently observed molecular cause of multidrug resistance (MDR). This multiple resistance represent...

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Detalles Bibliográficos
Autores principales: Bohacova, Viera, Seres, Mario, Pavlikova, Lucia, Kontar, Szilvia, Cagala, Martin, Bobal, Pavel, Otevrel, Jan, Brtko, Julius, Sulova, Zdena, Breier, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100532/
https://www.ncbi.nlm.nih.gov/pubmed/29723984
http://dx.doi.org/10.3390/molecules23051053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100532/
https://www.ncbi.nlm.nih.gov/pubmed/29723984
http://dx.doi.org/10.3390/molecules23051053

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