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Aleuritolic Acid Impaired Autophagic Flux and Induced Apoptosis in Hepatocellular Carcinoma HepG2 Cells

Aleuritolic acid (AA) is a triterpene that is isolated from the root of Croton crassifolius Geisel. In the present study, the cytotoxic effects of AA on hepatocellular carcinoma cells were evaluated. AA exerted dose- and time-dependent cytotoxicity by inducing mitochondria-dependent apoptosis in the...

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Detalles Bibliográficos
Autores principales: Yi, Hua, Wang, Kun, Du, Biaoyan, He, Lina, HO, Hiuting, Qiu, Maosong, Zou, Yidan, Li, Qiao, Jin, Junfeng, Zhan, Yujuan, Zhao, Zhongxiang, Liu, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100546/
https://www.ncbi.nlm.nih.gov/pubmed/29865221
http://dx.doi.org/10.3390/molecules23061338