Cargando…
Aleuritolic Acid Impaired Autophagic Flux and Induced Apoptosis in Hepatocellular Carcinoma HepG2 Cells
Aleuritolic acid (AA) is a triterpene that is isolated from the root of Croton crassifolius Geisel. In the present study, the cytotoxic effects of AA on hepatocellular carcinoma cells were evaluated. AA exerted dose- and time-dependent cytotoxicity by inducing mitochondria-dependent apoptosis in the...
Autores principales: | Yi, Hua, Wang, Kun, Du, Biaoyan, He, Lina, HO, Hiuting, Qiu, Maosong, Zou, Yidan, Li, Qiao, Jin, Junfeng, Zhan, Yujuan, Zhao, Zhongxiang, Liu, Xiaodong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100546/ https://www.ncbi.nlm.nih.gov/pubmed/29865221 http://dx.doi.org/10.3390/molecules23061338 |
Ejemplares similares
-
N-Methylparoxetine Blocked Autophagic Flux and Induced Apoptosis by Activating ROS-MAPK Pathway in Non-Small Cell Lung Cancer Cells
por: Wang, Kun, et al.
Publicado: (2019) -
Blockage of Autophagic Flux and Induction of Mitochondria Fragmentation by Paroxetine Hydrochloride in Lung Cancer Cells Promotes Apoptosis via the ROS-MAPK Pathway
por: Wang, Kun, et al.
Publicado: (2020) -
The Novel Autophagy Inhibitor Alpha-Hederin Promoted Paclitaxel Cytotoxicity by Increasing Reactive Oxygen Species Accumulation in Non-Small Cell Lung Cancer Cells
por: Zhan, Yujuan, et al.
Publicado: (2018) -
Berberine-induced apoptotic and autophagic death of HepG2 cells requires AMPK activation
por: Yu, Rong, et al.
Publicado: (2014) -
Dioscin Inhibits the Invasion and Migration of Hepatocellular Carcinoma HepG2 Cells by Reversing TGF-β1-Induced Epithelial-Mesenchymal Transition
por: Chen, Bonan, et al.
Publicado: (2019)