Multicomponent Domino Synthesis, Anticancer Activity and Molecular Modeling Simulation of Complex Dispirooxindolopyrrolidines

A series of spirooxindolopyrrolidine fused N-styrylpiperidone heterocyclic hybrids has been synthesized in excellent yield via a domino multicomponent protocol that involves one-pot three component 1,3-dipolar cycloaddition and concomitant enamine reactions performed in an inexpensive ionic liquid,...

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Detalles Bibliográficos
Autores principales: Arumugam, Natarajan, Almansour, Abdulrahman I., Suresh Kumar, Raju, Govindasami, Periyasami, Al-thamili, Dhaifallah M., Krishnamoorthy, Rajapandian, Periasamy, Vaiyapuri Subbarayan, Alshatwi, Ali A., Mahalingam, S. M., Thangamani, Shankar, Menéndez, J. Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100567/
https://www.ncbi.nlm.nih.gov/pubmed/29734741
http://dx.doi.org/10.3390/molecules23051094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100567/
https://www.ncbi.nlm.nih.gov/pubmed/29734741
http://dx.doi.org/10.3390/molecules23051094

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