Development of Validated and Stability-Indicating LC-DAD and LC-MS/MS Methods for Determination of Avanafil in Pharmaceutical Preparations and Identification of a Novel Degradation Product by LCMS-IT-TOF

Avanafil (AVA), one of the most effective drugs prescribed for erectile dysfunction, is a pyrimidine-derivative PDE5 inhibitor. In the current work, new LC methods were developed and validated for quantitative determination of avanafil and qualitative determination of its degradation products. The q...

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Detalles Bibliográficos
Autor principal: CAN, Nafiz Öncü
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100578/
https://www.ncbi.nlm.nih.gov/pubmed/30029473
http://dx.doi.org/10.3390/molecules23071771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100578/
https://www.ncbi.nlm.nih.gov/pubmed/30029473
http://dx.doi.org/10.3390/molecules23071771

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