Asymmetric Primaquine and Halogenaniline Fumardiamides as Novel Biologically Active Michael Acceptors

Novel primaquine (PQ) and halogenaniline asymmetric fumardiamides 4a–f, potential Michael acceptors, and their reduced analogues succindiamides 5a–f were prepared by simple three-step reactions: coupling reaction between PQ and mono-ethyl fumarate (1a) or mono-methyl succinate (1b), hydrolysis of PQ...

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Detalles Bibliográficos
Autores principales: Rajić, Zrinka, Beus, Maja, Michnová, Hana, Vlainić, Josipa, Persoons, Leentje, Kosalec, Ivan, Jampílek, Josef, Schols, Dominique, Keser, Toma, Zorc, Branka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100582/
https://www.ncbi.nlm.nih.gov/pubmed/30011922
http://dx.doi.org/10.3390/molecules23071724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100582/
https://www.ncbi.nlm.nih.gov/pubmed/30011922
http://dx.doi.org/10.3390/molecules23071724

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