Targeting GLI Transcription Factors in Cancer

Aberrant activation of hedgehog (Hh) signaling has been observed in a wide variety of tumors and accounts for more than 25% of human cancer deaths. Inhibitors targeting the Hh signal transducer Smoothened (SMO) are widely used and display a good initial efficacy in patients suffering from basal cell...

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Detalles Bibliográficos
Autores principales: Didiasova, Miroslava, Schaefer, Liliana, Wygrecka, Malgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100584/
https://www.ncbi.nlm.nih.gov/pubmed/29695137
http://dx.doi.org/10.3390/molecules23051003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100584/
https://www.ncbi.nlm.nih.gov/pubmed/29695137
http://dx.doi.org/10.3390/molecules23051003

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