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Zinc (II)-Mediated Selective O-Benzylation of 2-Oxo-1,2-Dihydropyridines Systems

The selective O-benzylation of 2-oxo-1,2-dihydropyridines plays a critical role in organic synthesis of natural products and biological active molecules. Herein we report a novel ternary system of ZnO, ZnCl(2) and N,N-diisopropylethylamine (DIEA), that is highly effective for selective O-benzylation...

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Detalles Bibliográficos
Autores principales: Zhou, Qifan, Du, Fangyu, Liang, Xinjie, Liu, Wenqiang, Fang, Ting, Chen, Guoliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100589/
https://www.ncbi.nlm.nih.gov/pubmed/30036939
http://dx.doi.org/10.3390/molecules23071784